More families come forward after their children suffer inflammatory disease linked to coronavirus

More ‘petrified’ parents have come forward after their children were struck down with tell-tale signs of a mysterious coronavirus-linked inflammatory syndrome that has hospitalised at least 20 youngsters and left a dozen fighting for their lives.

An alert was issued by NHS bosses on Tuesday warning GPs there had been a surge in youngsters needing intensive care after falling seriously unwell with the illness which causes a fatal immune overreaction.

Health Secretary Matt Hancock said he was ‘very worried’ by the mystery syndrome which experts think is caused by coronavirus infection. The illness appears to be similar to Kawasaki disease – which causes blood vessels to become inflamed, and toxic shock syndrome – an overreaction by the immune system which causes the body to attack its own organs.    

Six British families have come forward after their children suffered symptoms of the serious condition – some of whom were never tested for COVID-19, leaving them in the dark about whether their illness was linked to the virus.

Gemma Brown, from Droitwich Spa, Worcestershire, told MailOnline her two-year-old son Bertie was admitted to hospital last month on his second birthday when his temperature soared over 40C (104F) and his blotchy rash began to turn black. 

Mrs Brown says she is certain her boy had the vicious virus but has no way of knowing because he was denied a test and diagnosed with the rare Kawasaki disease.

Melanie Cook, 38, from Gypsyville, Hull, revealed her one-year-old son George was infected with coronavirus when he was struck down with mystery symptoms in mid-March. 

She said she was ‘110 per cent sure’ her son’s red eyes, violent vomiting and fatigue was COVID-19-related, but claims her son was diagnosed with conjunctivitis and denied a swab. 

Parents Sabrina and Steve Legge, from Bath, Somerset, have been left petrified that sons Dylan, 16, and Colston, 14, have the inflammatory syndrome after suffering from sickness, blisters on their tongues, diarrhoea and stabbing chest pains last week. The family claim their GP has refused to test the teens for coronavirus. 

A mother from Lancashire, who does not wish to be named, shared shocking images of her two-year-old daughter with blotchy purple rashes across her entire body. The parent said she was waiting on coronavirus test results with bated breath.

And Lewis Greig, 13, from Aberdeen, was finally diagnosed with the lethal virus after becoming so ill he needed to be hooked up to a ventilator. The teenager initially was struck down with inflammatory symptoms including bloodshot eyes and measles-like rashes.

A mother from Lancashire, who does not wish to be named, shared shocking images of her two-year-old daughter with blotchy purple rashes across her entire body

Bertie Brown was admitted to Worcestershire Royal hospital last month on his second birthday after developing a fever and rash across his body

Bertie Brown was admitted to Worcestershire Royal hospital last month on his second birthday after developing a fever and rash across his body

Melanie Cook, 38, from Gypsyville, Hull, believes her one-year-old son George was struck down with the mystery disease in mid-March after suffering red, puffy eyes (shown), 'violent vomiting' and fatigue.

Melanie Cook, 38, from Gypsyville, Hull, believes her one-year-old son George was struck down with the mystery disease in mid-March after suffering red, puffy eyes (shown), ‘violent vomiting’ and fatigue.

Lewis Greig, from Torry, Aberdeen, has been on a ventilator at the Royal Hospital for Children, Glasgow, after he suddenly became unwell last week with a high temperature.

But Lewis's condition became gradually worse, and he began to show other symptoms, including a rash, red swollen eyes and vomiting. He went on to developed a measles-like rash on his hands.

Lewis Greig, from Torry, Aberdeen, has been on a ventilator at the Royal Hospital for Children, Glasgow, after he suddenly became unwell last week with a high temperature (pictured: Lewis, left, and the rash which appeared on his hand, right)

Colston, 14, in bed after being struck down with the mystery illness

Dylan, 16, curls up into a ball on the couch after suffering the symptoms

Parents Sabrina and Steve Legge, from Bath, Somerset, have been left petrified that sons Colston (left), 14, and Dylan (right), 16,have the inflammatory syndrome after suffering from sickness, blisters on their tongues, diarrhoea and stabbing chest pains last week

The condition is a form of toxic shock syndrome which causes the body’s immune system to attack its own organs

The condition is a form of toxic shock syndrome which causes the body’s immune system to attack its own organs

WHAT IS KAWASAKI DISEASE AND TOXIC SHOCK SYNDROME? 

KAWASAKI DISEASE

Kawasaki disease is a condition that causes inflammation in the walls of the blood vessels and affects mostly children under five years old.

The inflammation can weaken the coronary arteries, which supply the heart with blood. This can lead to aneurysms and heart attacks.

The condition affects eight children out of every 100,000 and statistics show it is fatal in three per cent of cases that go untreated. 

WHAT SYMPTOMS DOES IT CAUSE?

The symptoms of Kawasaki disease usually develop in three phases over a six-week period, according to advice on the NHS’ website.

The first signs are a fever and a rash in the first few weeks, followed by the eyes of children becoming red and swollen. 

It can also cause the lips to dry up and crack, a sore throat, swollen lymph glands and the tongue to become red, the NHS warns. 

The second phase of Kawasaki disease often causes symptoms such as abdominal pain, vomiting, diarrhoea, headaches, joint pain and jaundice. 

In the third phase, symptoms tend to disappear but children ‘may still have a lack of energy and become easily tired during this time’. 

TOXIC SHOCK SYNDROME

Toxic shock syndrome is a highly dangerous bacterial infection – but it can be misdiagnosed because the symptoms are similar to other illnesses and because it is so rare.

It occurs when usually harmless staphylococcus aureus or streptococcus bacteria, which live on the skin, invade the bloodstream and release dangerous toxins.

TSS has a mortality rate of between five and 15 per cent. And reoccurs in 30-to-40 per cent of cases.

Using tampons is a particular risk factor for TSS, according to the NHS. 

WHAT SYMPTOMS DOES IT CAUSE?

  • a high temperature
  • flu-like symptoms
  • feeling and being sick
  • diarrhoea
  • a widespread sunburn-like rash
  • lips, tongue and the whites of the eyes turning a bright red
  • dizziness or fainting
  • difficulty breathing
  • confusion

Lewis Greig was not thought to have the virus because he did not have the usual dry cough but he is now on an intensive care ward at the Royal Hospital for Children in Glasgow.

Although Lewis has not been diagnosed with this toxic shock syndrome, medics have been warned to mindful of inflammatory symptoms such as his which could be linked to the coronavirus.  

Lewis’s mother Karen Simpson said the teenager had suffered from vomiting, rashes and red swollen eyes. He was rushed to hospital in Aberdeen before being transferred to an intensive care unit in Glasgow, where he tested positive for coronavirus. 

Lewis is in a critical but stable condition and is showing signs of improvement, although his family must wear protective equipment while visiting.

Ms Simpson spoke about Lewis’s ordeal to warn parents that children with COVID-19 can show different symptoms to adults.

Ms Simpson, who is currently staying in a Glasgow hotel to be close to her son, with Lewis’s father Wayne, 47, said: ‘It all started last Saturday when we discovered he had a temperature. It was really high – about 40.5 degrees.

‘At first we didn’t think it was anything too major. We assumed he had a bug and that it would pass.

‘On the Sunday though, things weren’t any better and Lewis started to get progressively worse as the week went on.

‘He started being sick, had a sore head and was really tired. We’d already been on the phone to the COVID-19 hub on 111 and they said to make sure he was drinking – if they needed to admit him they would.

‘By Thursday, he had developed a measles-like rash on his hands and his eyes went deep red and bloodshot.

‘On Friday morning, he woke up in a bad way. We phoned the doctor, who had a quick look at him and they phoned the sick kids’ hospital.

‘We took him up straight away, and when we got there, he couldn’t walk from the car into the building.’

Within hours of being taken to hospital, Lochside Academy pupil Lewis had been put on a ventilator to help him breathe.

And in the early hours of Saturday, he was transferred to Glasgow by ambulance.

Ms Simpson said: ‘I have never seen anything like it before. It was so scary. The first few tests they did came back negative for COVID-19. But then they did another one and that came back positive on Sunday night.’

Ms Simpson now wants to make other parents aware of tell-tale signs which may show children are suffering from the virus.

She said: ‘I want to help other parents understand how to spot it. They might show some really strange symptoms which aren’t fitting with the normal coronavirus symptoms. Make sure you get them checked and keep pushing to have them tested.

‘One of the doctors said to us children don’t present with a dry cough like adults do. In children, there’s an inflammatory reaction which makes it look like an autoimmune disease.’

Lewis, who is a brother to Nathan, Sam, Abby, Jorja and Eli, is now showing small signs of progress – and his family are determined to help him pull through.

Ms Simpson said: ‘Lewis is now making small steady steps towards getting better, although he is still having to have quite a lot of medication and is still on a ventilator.

‘He’s able to move now and knows when we go into his room, although we can’t have very much contact with him and need to wear PPE.

His temperature soared over 40C (104F) and the blotchy rash spread across his body and began to turn black. Doctors were initially baffled but a senior consultant eventually diagnosed the boy with the rare Kawasaki disease

His temperature soared over 40C (104F) and the blotchy rash spread across his body and began to turn black. Doctors were initially baffled but a senior consultant eventually diagnosed the boy with the rare Kawasaki disease

His mother Gemma (pictured with Bertie and is older brother George, 14) believes his symptoms were a complication of the coronavirus

But Bertie was not given a COVID-19 test, leaving both medics and his family in the dark about a possible link

His mother Gemma (pictured with Bertie and is older brother George, 14) believes his symptoms were a complication of the coronavirus. But Bertie (right) was not given a COVID-19 test, leaving both medics and his family in the dark about a possible link

The UK's total number of coronavirus deaths and infections per day

The UK’s total number of coronavirus deaths and infections per day

The UK is still tracking on the same kind of course as outbreaks in France, Italy and Spain - although the figures are not exactly comparable

The UK is still tracking on the same kind of course as outbreaks in France, Italy and Spain – although the figures are not exactly comparable

‘But he is showing some positive signs and he is definitely in the right place. He will get through this because he is a fighter.’

Gemma Brown, 38, told MailOnline that her son, Bertie, was admitted to Worcestershire Royal hospital last month on his second birthday, when his temperature soared over 40C (104F) and his blotchy rash began to turn black.

Doctors were initially baffled but a senior consultant eventually diagnosed the boy with the rare Kawasaki disease, a form of toxic shock syndrome which causes the body’s immune system to attack its own organs.

But Bertie was not given a COVID-19 test, leaving both medics and his family in the dark about a possible link between Kawasaki disease and coronavirus.

‘I don’t know how the Government is going to prove there’s a link if they’re not testing patients,’ the mother-of-two from Droitwich Spa, Worcestershire, said.

‘I asked for him to be tested, as I had a gut feeling that there was a connection between covid and Kawasaki. Both attack your immune system and the whole family had been poorly with Covid symptoms before Bertie fell ill.

‘I was adamant that there was a link and was begging for a test, but they just told me that there was no need to test the under-fives.’

The boy was given an immunoglobin transfusion and was in hospital for five days. ‘It was horrific seeing him like that,’ Mrs Brown said.

‘He didn’t have any respiratory problems but he was put in a ward on his own and he was easily the most poorly child in the hospital.

‘His rash had started out being itchy, but it quickly put him in agony. His temperature was dangerously high and they were monitoring him round the clock.’

Bertie, who was born very prematurely weighing only 1.5lb, has always had a weak immune system, making him susceptible to viruses.

‘Thank God he is OK now and has come home, though he’s still on Aspirin to prevent his blood clotting,’ his mother said.

‘He’s much better in himself. But the fact is that we just don’t know what’s been going on as he wasn’t tested for coronavirus.’

NHS doctors have been warned to look out for severe reactions in children – including symptoms like Bertie’s.

An urgent alert issued by NHS England said there was a ‘growing concern’ a COVID-19-related inflammatory syndrome was emerging, a rare form of toxic shock which is said to be similar to Kawasaki disease.

Doctors were yesterday issued an alert about a sharp rise in the number of infants being admitted to intensive care across the UK with the ‘inflammatory syndrome’ over the past three weeks. Most of the children affected already have Kawasaki disease, NHS sources said.

Health chiefs today insisted they are ‘unaware’ of any deaths in British children from the inflammatory syndrome – despite Matt Hancock admitting that ‘some’ youngsters have mysteriously died with no underlying conditions.  

Doctors were yesterday issued an alert about a sharp rise in the number of infants being admitted to intensive care across the UK with the Kawasaki-like disease. 

Officials have refused to say how many British children have been affected by the illness but up to 20 have fallen critically unwell, according to reports. One child needed to be put on a form of life support after their heart and lungs began to fail. The majority of the patients are thought to be under the age of five. 

The illness appears to be similar to Kawasaki disease – which causes blood vessels to become inflamed, and toxic shock syndrome – an overreaction by the immune system which causes the body to attack its own organs.  

The Health Secretary was quizzed on LBC about the inflammatory syndrome and admitted he was ‘very worried’ by the mysterious complication. He was also asked about how many children had died from coronavirus. 

Mr Hancock originally said all the deceased youngsters had ‘significant underlying health conditions’ but then backtracked immediately after host Nick Ferrari questioned him about the new inflammatory illness that had prompted the national alert. Mr Hancock then admitted ‘some’ children with no health woes had succumbed to COVID-19. 

The Department of Health today insisted that Mr Hancock was not referring to children who have died from the inflammatory syndrome potentially linked to the disease – and was discussing COVID-19 deaths in general.   

Officials have yet to offer any clarity on exactly what the symptoms are, despite pleas from paediatricians to paint a clearer picture so they can look out for them. Kawasaki disease and toxic shock syndrome, combined, cause harmful internal swelling, fever and breathing problems – all hallmark signs of COVID-19. 

Officials told the PA news agency fewer than 20 children in England have been admitted to hospital with the mysterious syndrome. 

Doctors have compared it to toxic shock syndrome and Kawasaki disease which, combined, cause harmful internal swelling, fever and breathing problems – all signs of coronavirus.

But some of the children needing intensive care have tested negative for COVID-19, further complicating the diagnosis and raising questions that another pathogen could be behind the condition.  

Officials have yet to offer any clarity on what the symptoms are, despite pleas from paediatricians to paint a clearer picture so they can look out for them.

It is not clear how many children have had the inflammatory syndrome, nor how many have died with it. It is also unclear how old the children have been.  

However, most of the children affected by the inflammatory syndrome already have Kawasaki disease, an NHS source told The Guardian. 

Kawasaki disease is a condition that causes inflammation in the walls of the blood vessels and affects mostly children under five years old. 

There are roughly eight cases for every 100,000 children in the UK and statistics show it is fatal in three per cent of cases that go untreated.

The new COVID-19-linked cases are occurring when someone with Kawasaki disease contracts the virus and it produces complications, the source told the newspaper. 

Children are not thought to be badly affected by COVID-19 – very few youngsters have died around the world since the pandemic began in December. 

Their apparent resilience to the disease has baffled doctors for weeks because they are often ‘super-spreaders’ of viral illnesses such as flu.

But children being seen with this syndrome often suffer from stomach pain, heart inflammation and ‘gastrointestinal symptoms’ – which could include vomiting and diarrhoea.

NHS medical director Professor Stephen today urged parents who are worried about a child who is sick and not recovering to seek medical help.

Chief medical officer Professor Chris Whitty said yesterday is ‘entirely plausible’ this spike is linked to the COVID-19 outbreak. 

Speaking at No 10’s press briefing yesterday, he added: ‘Because we know that in adults who of course have much more disease than children do, big problems are caused by an inflammatory process and this looks rather like an inflammatory process, a rather different one.

‘Therefore, given that we have got a new presentation of this at a time with a new disease, the possibility – it is not a definite, we need to look for other causes as well – but the possibility that there is a link is certainly plausible.’